Recombinant SERPING1 from MYBIOSOURCE INC.
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| Product Name | Recombinant SERPING1 |
| Description | Sequence: 23-500aa. Purity >90% by SDS-PAGE. SERPING1, also known as plasma protease C1 inhibitor, is a protease inhibitor belonging to the serpin superfamily. This protein is the physiological inhibitor of activated C1r and C1s, two serine proteases involved in the classical complement pathway. Also, it has a 2-domain structure, unlike most family members. The C-terminal serpin domain is similar to other serpins, and this part of this inhibitor provides the inhibitory activity. C1-inhibitor is highly glycosylated, bearing both N- and O-glycans. Deficiency of this protein results in hereditary angioedema, which is characterized by recurrent episodes of localized angioedema of the skin, gastrointestinal mucosa or upper respiratory mucosa. I. MW: 54.2kDa (489aa); 70-100kDa (SDS-PAGE under reducing conditions) |
| Size | 0.05 mg, 0.25 mg |
| Concentration | 1.0mg/ml (determined by Absorbance at 280nm) |
| Applications | SDS-PAGE |
| Other Names | [Plasma protease C1 inhibitor; SERPING1; C1IN; C1INH; C1NH; HAE1; HAE2], [SERPING1; SERPING1; C1IN; C1NH; HAE1; HAE2; C1INH; C1IN; C1NH; C1 Inh; C1Inh] |
| Gene, Accession, CAS # | [SERPING1], Gene ID: 710, NCBI: NP_000053.2, UniProt: P05155 |
| Catalog # | MBS201094 |
| Price | $310, $925 |
| Order / More Info | Recombinant SERPING1 from MYBIOSOURCE INC. |
| Product Specific References | Frangi D., et al, (1992) FEBS Lett. 301:34-36. Davis AE., et al, (2004) Drug News Perspect 17:439. |
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