A-674563 from MYBIOSOURCE INC.
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| Product Name | A-674563 |
| Description | Purity >98%. A-674563 is a B/Akt inhibitor with an IC50 of 14 nM and also shows inhibitory activity against PKA and CDK2 with IC50 of 16 and 46 nM, respectively. MW: 358.4 |
| Size | 5 mg, 1 mL (in DMSO), 10 mg |
| Concentration | 0.1 mM: 27.9 mL (1 mg); 139.51 mL (5 mg); 279.02mL (10 mg). 0.5 mM: 5.58 mL (1 mg); 27.9 mL (5 mg); 55.8 mL (10 mg). 1 mM: 2.79 mL (1 mg); 13.95 mL (5 mg); 27.9 mL (10 mg). 5 mM: 0.56 mL (1 mg); 2.79 mL (5 mg); 5.58 mL (10 mg) |
| Applications | n/a |
| Other Names | n/a |
| Gene, Accession, CAS # | CAS: 552325-73-2 |
| Catalog # | MBS384090 |
| Price | $200, $215, $275 |
| Order / More Info | A-674563 from MYBIOSOURCE INC. |
| Product Specific References | Kobayashi T,.et al. A-674563 increases chondrocyte marker expression in cultured chondrocytes by inhibiting Sox9 degradation, Biochem Biophys Res Commun, 2018, Jan 1;495(1):1468-1475 PMID: 29196261Lin Xu,.et al. Concurrent targeting Akt and sphingosine kinase 1 by A-674563 in acute myeloid leukemia cells, Biochem Biophys Res Commun, 2016, Apr 15;472(4):662-8 PMID: 26920060Zou Y,.et al. Pre-clinical assessment of A-674563 as an anti-melanoma agent, Biochem Biophys Res Commun, 2016, Aug 12;477(1):1-8 PMID: 26970307 |
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