Edit |   |
---|---|
Product Name | Recombinant Human Angiotensin-Converting Enzyme 2 (ACE2), Partial, active protein |
Description | Sequence: 18-740aa; Partial. Purity >95% as determined by SDS-PAGE. Relevance: Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don't inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function. |
Size | 0.01 mg (Mammalian-Cell), 0.05 mg (Mammalian-Cell), 0.5 mg (Mammalian-Cell) |
Concentration | n/a |
Applications | n/a |
Other Names | [Angiotensin-Converting Enzyme 2; ACE-Related Carboxypeptidase; Angiotensin-Converting Enzyme Homolog; ACEH; Metalloprotease MPROT15; ACE2] |
Gene, Accession, CAS # | [ACE2], Gene ID: 59272, NCBI: NP_068576.1, UniProt: Q9BYF1 |
Catalog # | MBS7115164 |
Price | $175, $425, $1600 |
Order / More Info | Recombinant Human Angiotensin-Converting Enzyme 2 (ACE2), Partial, active protein from MYBIOSOURCE INC. |
Product Specific References | n/a |