ABT-751 from MYBIOSOURCE INC.
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| Product Name | ABT-751 |
| Description | Purity >99%. ABT-751 is a novel bioavailable tubulin-binding and antimitotic sulfonamide agent with IC50 of about 1.5 and 3.4 uM in neuroblastoma and non-neuroblastoma cell lines, respectively. ABT-751 binds to the colchicine-binding site on beta-tubulin and inhibits the polymerization of microtubules, thereby preventing tumor cell replication. In preclinical studies, ABT-751 showed antitumor activity against a broad spectrum of tumor lines and human xenograft models (colon, nasopharyngeal, lung, stomach, breast, pancreas, prostate). ABT-751 is active against cell lines resistant to vincristine, doxorubicin, and cisplatin. ABT-751 also disrupts tumor neovascularization, reducing tumor blood flow and so inducing a cytotoxic effect. ABT-751 i. MW: 371.41 |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | n/a |
| Gene, Accession, CAS # | [ABT-751] |
| Catalog # | MBS8506497 |
| Price | $410 |
| Order / More Info | ABT-751 from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.