Recombinant Human DNA ligase 4 (LIG4) , partial from MYBIOSOURCE INC.

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Product NameRecombinant Human DNA ligase 4 (LIG4) , partial
DescriptionSequence: 654-911. Partial. Purity >85% (SDS-PAGE). This protein is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK). Both XRCC4 and DNA-PK are known to be required for NHEJ. The crystal structure of the complex formed by this protein and XRCC4 has been resolved. Defects in this gene are the cause of LIG4 syndrome. Alternatively spliced transcript variants encoding the same protein have. MW: 103,971 Da
Size0.05 mg (E. coli), 0.05 mg (Yeast), 0.2 mg (E. coli)
Concentrationn/a
Applicationsn/a
Other Names[DNA ligase 4 isoform 1; DNA ligase 4; DNA ligase 4; DNA ligase 4; DNA ligase IV; Polydeoxyribonucleotide synthase [ATP] 4], [LIG4; LIG4; LIG4S]
Gene, Accession, CAS #[LIG4], Gene ID: 3981, NCBI: NP_001091738.1, UniProt: P49917
Catalog #MBS951845
Price$660, $800, $885
Order / More InfoRecombinant Human DNA ligase 4 (LIG4) , partial from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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