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Product Name | CD40:Fc, Recombinant, Human (Tumor Necrosis Factor Receptor Superfamily Member 5, TNFRSF5, CD40L Receptor) |
Description | Highly Purified. >95% (SDS-PAGE). CD40 belongs to the TNF-receptor superfamily and is essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development and germinal center formation. The interaction of CD40-CD40L is necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is constitutively expressed by antigen presenting cells, including dendritic cells, B cells and macrophages. Consistent with its widespread expression on normal cells, CD40 is also expressed on a wide range of tumor cells, including non-Hodgkin's and Hodgkin's lymphomas, myeloma and some carcinomas. MW: ~54kD (SDS-PAGE) |
Size | 0.05 mg |
Concentration | n/a |
Applications | n/a |
Other Names | [Complement C1q subcomponent subunit B; Complement C1q subcomponent subunit B; complement C1q subcomponent subunit B; complement component 1, q subcomponent, beta polypeptide], [C1qb; C1qb] |
Gene, Accession, CAS # | Gene ID: 12260, NCBI: P14106.2, UniProt: P14106 |
Catalog # | MBS636995 |
Price | $505 |
Order / More Info | CD40:Fc, Recombinant, Human (Tumor Necrosis Factor Receptor Superfamily Member 5, TNFRSF5, CD40L Receptor) from MYBIOSOURCE INC. |
Product Specific References | n/a |