Edit |   |
---|---|
Product Name | CD320, 31-229aa, Human, hIgG-His-tag, Baculovirus |
Description | Purity > 90% by SDS-PAGE. CD320, also known as CD320 antigen isoform 1, belongs to the low-density lipoprotein receptor family, with 2 low-density lipoprotein receptor type A domains separated by a complement-like cysteine-rich region. It binds TC- cobalamin (Cbl) and internalizes the complex by endocytosis. It is known to enhance proliferation of germinal center (GC) B cells and follicular dendritic cells. It augments the proliferation of PC precursors generated by IL-10. It collaborates with CD44 in supporting lymphomagenesis by a Burkitt lymphoma cell line, L3055. Recombinant human CD320, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. MW: 47.4kDa (438aa) 57-70kDa (SDS-PAGE under reducing conditions) |
Size | 0.05 mg, 0.25 mg |
Concentration | 0.5 mg/ml (determined by Absorbance at 280nm) |
Applications | SDS-PAGE |
Other Names | [CD320 antigen isoform 1; CD320; 8D6; 8D6A; TCBLR], [CD320; CD320; 8D6; 8D6A; TCBLR; 8D6A; TCblR] |
Gene, Accession, CAS # | [CD320], Gene ID: 51293, NCBI: NP_057663, UniProt: Q9NPF0 |
Catalog # | MBS206645 |
Price | $310, $925 |
Order / More Info | CD320, 31-229aa, Human, hIgG-His-tag, Baculovirus from MYBIOSOURCE INC. |
Product Specific References | Quadros EV., et al. (2009) Blood. 113:186-192.; Zhang X., et al. (2001) J Immunol. 167:49-56. |