Recombinant Complement Factor B from MYBIOSOURCE INC.
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| Product Name | Recombinant Complement Factor B |
| Description | Sequence: 260-764aa. Purity > 90% by SDS - PAGE. Complement factor B, also known as CFB, is a component of the alternative pathway of complement activation.Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, itis cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The activesubunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb isinvolved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. Recombinant human Complement factor B protein, fused to His-tag at C-terminus, was expressed in insect cell and purified byusing conventional chromatography techniq. MW: 58.1kDa (514aa) |
| Size | 0.05 mg, 0.1 mg, 0.5 mg |
| Concentration | 0.5mg/ml (determined by Absorbance at 280nm) |
| Applications | SDS-PAGE |
| Other Names | [CFB; C3/C5 convertase; Glycine-rich beta glycoprotein; GBG; PBF2; Properdin factor B; BF; BFD; AHUS4; ARMD14; CFAB; CFBD; FB; FBI12; GBG; H2-Bf], [CFB; CFB; BF; FB; BFD; GBG; CFAB; CFBD; PBF2; AHUS4; FBI12; H2-Bf; ARMD14; BF; BFD; GBG] |
| Gene, Accession, CAS # | Gene ID: 629, NCBI: NP_001701.2, UniProt: P00751 |
| Catalog # | MBS201168 |
| Price | $405, $610, $1610 |
| Order / More Info | Recombinant Complement Factor B from MYBIOSOURCE INC. |
| Product Specific References | Francis PJ., et al. (2009) J Med Genet. 46:300-307.;;Schwaeble W., et al (1993). Immunobiology 188:221-232. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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