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Product Name | Recombinant Human Plasminogen (PLG), Partial |
Description | Sequence: 274-560aa; Partial. Purity >85% as determined by SDS-PAGE. Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells. Angiostatin is an angiogenesis inhibitor that blocks neovascularization and. MW: 36.0 kDa |
Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli) |
Concentration | n/a |
Applications | n/a |
Other Names | [plasminogen isoform 1; Plasminogen; plasminogen; plasminogen] |
Gene, Accession, CAS # | [PLG], Gene ID: 5340, NCBI: NP_000292.1, UniProt: P00747 |
Catalog # | MBS7115243 |
Price | $160, $200, $295 |
Order / More Info | Recombinant Human Plasminogen (PLG), Partial from MYBIOSOURCE INC. |
Product Specific References | Expression of recombinant human plasminogen and aglycoplasminogen in HeLa cells. Browne M.J., Chapman C.G., Dodd I., Carey J.E., Lawrence G.M.P., Mitchell D., Robinson J.H. Submitted (OCT-1991). |