EIF3I, 1-325aa, Human, His tag, E Coli (Denatured) from MYBIOSOURCE INC.
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| Product Name | EIF3I, 1-325aa, Human, His tag, E Coli (Denatured) |
| Description | Purity > 90% by SDS-PAGE. EIF3I is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2: GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AuG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Recombinant human EIF3I protein, fused to His-tag at N-te. MW: 38.9kDa (348aa) |
| Size | 0.1 mg, 0.5 mg |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| Applications | SDS-PAGE |
| Other Names | [eukaryotic translation initiation factor 3 subunit I; C3orf68], [EIF3I; EIF3I; TRIP1; EIF3S2; TRIP-1; PRO2242; eIF3-p36; eIF3-beta; eIF3i; TRIP-1] |
| Gene, Accession, CAS # | [EIF3I], Gene ID: 8668, NCBI: NP_003748, UniProt: Q13347 |
| Catalog # | MBS205266 |
| Price | $310, $720 |
| Order / More Info | EIF3I, 1-325aa, Human, His tag, E Coli (Denatured) from MYBIOSOURCE INC. |
| Product Specific References | Proshkin,S.A., et al. (2011) Biochemistry Mosc. 76 (8), 976-980; Perez,R.E., et al. (2011) Am. J. Physiol. Lung Cell Mol. Physiol. 300 (5), L799-L807; |
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