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Product Name | ABT-869 |
Description | Purity ≥99%. Background: ABT-869 is multi-targeted inhibitor of all members of the VEGF and PDGF receptor families (e.g., KDR, IC?? value of 4 nM), but has much less activity (IC?? values >1 uM) against unrelated receptor tyrosine kinases, soluble tyrosine kinases or serine/threonine kinases. The kinase inhibition profile of ABT-869 is evident in cellular assays of RTK phosphorylation (IC?? values of 2, 4 and 7 nM for PDGFRbeta, KDR and CSF-1R, respectively) and VEGF-stimulated proliferation (0.2 nM IC?? for human endothelial cells). MW: 375.41 |
Size | 1 mg, 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | CAS: 796967-16-3 |
Catalog # | MBS842781 |
Price | $205, $580 |
Order / More Info | ABT-869 from MYBIOSOURCE INC. |
Product Specific References | n/a |