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Product Name | ABI3, 1-366aa, Human, His tag, E Coli (Denatured) |
Description | Purity > 85% by SDS-PAGE. ABI3, also as known as ABI gene family member 3, belongs to the ABI family. This protein is a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain. The Abi family members are thought to negatively regulate cell growth and transformation, including cellular transformation through v-Abl as well as mediate cell motility by regulating actin polymerization in lamellipodia and filopodia. ABI3 inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. MW: 41.4 kDa (389aa) |
Size | 0.02 mg, 0.1 mg |
Concentration | 0.5 mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | [ABI family member 3; ABI family; member 3; NESH; SSH3BP3], [ABI3; ABI3; NESH; SSH3BP3; NESH; Nesh] |
Gene, Accession, CAS # | [ABI3], Gene ID: 51225, NCBI: NP_057512, UniProt: Q9P2A4 |
Catalog # | MBS204520 |
Price | $310, $720 |
Order / More Info | ABI3, 1-366aa, Human, His tag, E Coli (Denatured) from MYBIOSOURCE INC. |
Product Specific References | Ichigotani Y., et al. (2002) Cancer Res. 62:2215-2219; Miyazaki K, et al. (2000) Biochim Biophys Acta 1493 (1-2): 237-41. |