FANCL Recombinant protein from MYBIOSOURCE INC.
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| Product Name | FANCL Recombinant protein |
| Description | Recombinant full-length human FANCL was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. Scientific Background: FANCL or Fanconi anemia complementation group L is a member of the Fanconi anemia complementation group. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. FANCL is crucial in the FA pathway as the catalytic subunit required for monoubiquitination of FANCD2 (1). UBE2W interacts with FANCL and regulates the monoubiquitination of Fanconi anemia protein FANCD2 (2). MW: ~67 kDa |
| Size | 0.02 mg, 0.05 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Other Names | [FAAP43; PHF9; POG], [FAAP43; PHF9; POG] |
| Gene, Accession, CAS # | [FANCL], Gene ID: 55120, NCBI: NP_060532.2, UniProt: Q9NW38 |
| Catalog # | MBS515181 |
| Price | $270, $450 |
| Order / More Info | FANCL Recombinant protein from MYBIOSOURCE INC. |
| Product Specific References | 1. Meetei.et.al: A novel ubiquitin ligase is deficient in Fanconi anemia. Nature Genet. 35: 165-170, 2003.2. Zhang, Y.et.al: UBE2W interacts with FANCL and regulates the monoubiquitination of Fanconi anemia protein FANCD2. Molec. Cells 31: 113-122, 2011. |
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MYBIOSOURCE INC.
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