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Product Name | ABT-263 |
Description | Purity ≥98% by HPLC. Background: A potent, small molecule Bcl-2 family protein inhibitor (Ki's of <1 nmol/L for Bcl-2, Bcl-XL and Bcl-w). Displays anticancer properties. Selectively binds to apoptosis suppressor proteins Bcl-2, Bcl-XL, and Bcl-w and prevents their binding to the apoptotic effectors Bax and Bak proteins, which may trigger apoptosis in tumor cells overexpressing Bcl-2, Bcl-XL, and Bcl-w. MW: 974.61 |
Size | 5 mg, 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | CAS: 923564-51-6 |
Catalog # | MBS842652 |
Price | $245, $755 |
Order / More Info | ABT-263 from MYBIOSOURCE INC. |
Product Specific References | n/a |