CFB-Bb, 260-764aa, Human, His tag, E Coli (Denatured) from MYBIOSOURCE INC.
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| Product Name | CFB-Bb, 260-764aa, Human, His tag, E Coli (Denatured) |
| Description | Purity > 85% by SDS-PAGE. CFB encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. Recombinant human CFB-Bb protein, fused to His-tag at N-terminus, was expressed in E Coli. MW: 59.4kDa (528aa) |
| Size | 0.1 mg, 0.5 mg |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| Applications | SDS-PAGE |
| Other Names | [complement factor B; AHuS4; BF; BFD; CFAB; FB; FBI12; GBG; H2-Bf; PBF2], [CFB; CFB; BF; FB; BFD; GBG; CFAB; CFBD; PBF2; AHUS4; FBI12; H2-Bf; ARMD14; BF; BFD; GBG] |
| Gene, Accession, CAS # | [CFB-Bb], Gene ID: 629, NCBI: NP_001701, UniProt: P00751 |
| Catalog # | MBS204839 |
| Price | $310, $720 |
| Order / More Info | CFB-Bb, 260-764aa, Human, His tag, E Coli (Denatured) from MYBIOSOURCE INC. |
| Product Specific References | Wu,L., et al. (2013) Invest. Ophthalmol. Vis. Sci. 54 (1), 170-174; Thakkinstian,A., et al. (2012) Am. J. Epidemiol. 176 (5), 361-372; |
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