AAL-993 from MYBIOSOURCE INC.
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| Product Name | AAL-993 |
| Description | Purity ≥98% by TLC. Background: AAL-993 is a potent, selective and cell-permeable inhibitor of VEGFR-1 (IC?? = 130 nM), VEGFR-2 (IC?? = 23 nM) and VEGFR-3 (IC?? = 18nM). At higher concentrations it inhibits PDGFR (640 nM), c-Kit (236 nM) and CSF-1R (380 nM). Inactive at other kinases such as EGFR, FGFR-1, CDK-1, Tie-2, c-Met, IGF-1R, c-Src and c-Abl. X-ray crystal studies on AAL-993 complexed to the catalytic domain of diphosphorylated VEGFR- 2 indicates that it binds to an inactive conformation of the protein. AAL-993 inhibits VEGF-induced angiogenesis (mouse model). MW: 371.36 |
| Size | 2 mg, 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | n/a |
| Gene, Accession, CAS # | CAS: 269390-77-4 |
| Catalog # | MBS842171 |
| Price | $145, $385 |
| Order / More Info | AAL-993 from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.