Edit |   |
---|---|
Product Name | Complement C5a des Arg, Recombinant Human |
Description | Purified. Complement fragment C5a is a 74-residu glycopolypeptide which is generated by proteol ic cleavage of the complement factor 5 In the course of complement activation. C5a is a potent chemoattractant and anaphylatoxin that acts on all classes of leukocytes and on many other cell types including endothelial, smooth muscle, kidney, liver, and neural cells. In addition to its proinflammatory effects, C5a has been shown to protect cells against toxic insult and to stimulate proliferation in neurons and hep'atocytes, suggesting.a wider role for C5a in homeostasis. C5a is rapidly desarginated by serum carboxypeptidase N to the less potent derivate C5a desArg the first stage in deactivation of anaphylatoxin activity. The C5a desArg form has |
Size | 0.05 mg |
Concentration | ~0.1mg/ml (after reconstitution) |
Applications | n/a |
Other Names | [C5a anaphylatoxin chemotactic receptor 2; C5a anaphylatoxin chemotactic receptor 2; C5a anaphylatoxin chemotactic receptor 2; G protein-coupled receptor 77; G protein-coupled receptor C5L2; C5a anaphylatoxin chemotactic receptor C5L2; complement component 5a receptor 2; Complement component 5a receptor 2; G-protein coupled receptor 77], [C5AR2; C5AR2; C5L2; GPF77; GPR77; C5L2; GPR77] |
Gene, Accession, CAS # | Gene ID: 27202, NCBI: NP_001258679.1, UniProt: Q9P296 |
Catalog # | MBS637987 |
Price | $820 |
Order / More Info | Complement C5a des Arg, Recombinant Human from MYBIOSOURCE INC. |
Product Specific References | n/a |