Edit |   |
---|---|
Product Name | ICOSLG, 19-256aa, Human, hIgG-His-tag, Baculovirus |
Description | Purity > 90% by SDS-PAGE. ICOSLG, also known as ICOS ligand isoform a, is a number of the B7 family of co-stimulatory molecules related to B7-1 and B7-2. This protein is a transmembrane glycoprotein with extracellular IgV and IgC domains, and binds to ICOS on activated T cells. Its dependent signaling may play an active role in a proliferative response rather than in cytokine and chemokine production. Recombinant human ICOSLG, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. MW: 53.7kDa (480aa) 50-70kDa (SDS-PAGE under reducing conditions.) |
Size | 0.05 mg, 0.25 mg |
Concentration | 1 mg/ml (determined by Absorbance at 280nm) |
Applications | SDS-PAGE |
Other Names | [ICOS ligand isoform a; ICOSLG; B7-H2; B7H2; B7RP-1; B7RP1; CD275; GL50; ICOS-L; ICOSL; LICOS], [ICOSLG; ICOSLG; B7H2; GL50; B7-H2; B7RP1; CD275; ICOSL; LICOS; B7RP-1; ICOS-L; B7H2; B7RP1; ICOSL; KIAA0653; B7-H2; B7RP-1] |
Gene, Accession, CAS # | [ICOSLG], Gene ID: 23308, NCBI: NP_056074, UniProt: O75144 |
Catalog # | MBS206650 |
Price | $310, $925 |
Order / More Info | ICOSLG, 19-256aa, Human, hIgG-His-tag, Baculovirus from MYBIOSOURCE INC. |
Product Specific References | Maazi H., et al, (2015) Immunity 42:538-551.; Shen C., et al, (2014) Clin. Exp. Allergy 44:831-841. |