Edit |   |
---|---|
Product Name | Recombinant Bovine Adiponectin |
Description | Sequence: 18-240aa; Full Length of Mature Protein. Purity >90% as determined by SDS-PAGE. Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with d. MW: 40.4kD |
Size | 0.01 mg (Yeast), 0.05 mg (Yeast), 0.1 mg (Yeast) |
Concentration | n/a |
Applications | n/a |
Other Names | [30 kDa adipocyte complement-related protein; Adipocyte complement-related 30 kDa protein; ACRP30; Adipocyte, C1q and collagen domain-containing protein; Adipose most abundant gene transcript 1 protein; apM-1], [ADIPOQ; ADIPOQ; APM1; ACRP30; ACRP30; APM1; ACRP30; apM-1] |
Gene, Accession, CAS # | [ADIPOQ], Gene ID: 282865, NCBI: NP_777167.1, UniProt: Q3Y5Z3 |
Catalog # | MBS1366165 |
Price | $260, $360, $595 |
Order / More Info | Recombinant Bovine Adiponectin from MYBIOSOURCE INC. |
Product Specific References | Identification and adipocyte differentiation-dependent expression of the unique disialic acid residue in an adipose tissue-specific glycoprotein, adipo Q.Sato C., Yasukawa Z., Honda N., Matsuda T., Kitajima K.J. Biol. Chem. 276:28849-28856(2001) |