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Product Name | CD46, 35-313aa, Human, His tag, E Coli |
Description | Purity > 85% by SDS-PAGE. Membrane cofactor protein isoform 14, also known as CD46, is a type I membrane protein that has cofactor activity for inactivation of complement components C3b and C4b by serum factor I. This function resides in the complement control protein repeats (CCPs), with CCP1-4 essential for regulation. CD46 is widely distributed on thymocytes, T cells, B cells, monocytes, granulocytes, NK cells, platelets, endothelial cells, epithelial cells, fibroblasts, placenta and sperm, but not on erythrocyte. Recombinant human CD46 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques. MW: 33.8 kDa (302aa) confirmed by MALDI-TOF |
Size | 0.1 mg, 0.5 mg |
Concentration | 0.5 mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | [Membrane cofactor protein isoform 14; AHuS2; MCP; MIC10; TLX; TRA2.10], [CD46; CD46; MCP; TLX; AHUS2; MIC10; TRA2.10; MCP; MIC10] |
Gene, Accession, CAS # | [CD46], Gene ID: 4179, NCBI: NP_758860, UniProt: P15529 |
Catalog # | MBS205441 |
Price | $310, $720 |
Order / More Info | CD46, 35-313aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
Product Specific References | Riley R C., et al. (2002) Mol Reprod Dev. 62:534-546.; Iwata K., et al. (1995) J Biol Chem. 270:15148-15152.; |