Recombinant Human Adiponectin protein from MYBIOSOURCE INC.
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| Product Name | Recombinant Human Adiponectin protein |
| Description | Purity 90%. Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW. MW: 30 KD |
| Size | 0.01 mg, 0.05 mg, 0.2 mg |
| Concentration | n/a |
| Applications | ELISA, Western Blot |
| Other Names | [Homo sapiens adiponectin, C1Q and collagen domain containing (ADIPOQ), transcript variant 1, mRNA; Adiponectin; adiponectin; OTTHUMP00000210047; OTTHUMP00000210048; gelatin-binding protein 28; adipose specific collagen-like factor; 30 kDa adipocyte complement-related protein; adipocyte complement-related 30 kDa protein; adipose most abundant gene transcript 1 protein; adiponectin, C1Q and collagen domain containing; 30 kDa adipocyte complement-related protein; Adipocyte complement-related 30 kDa protein; ACRP30; Adipocyte, C1q and collagen domain-containing protein; Adipose most abundant gene transcript 1 protein; apM-1; Gelatin-binding protein], [ADIPOQ; ADIPOQ; ACDC; ADPN; APM1; APM-1; GBP28; ACRP30; ADIPQTL1; ACDC; ACRP30; APM1; GBP28] |
| Gene, Accession, CAS # | Gene ID: 9370, NCBI: NP_001171271.1, UniProt: Q15848 |
| Catalog # | MBS717060 |
| Price | $130, $220, $770 |
| Order / More Info | Recombinant Human Adiponectin protein from MYBIOSOURCE INC. |
| Product Specific References | [1] Adiponectin multimerization is dependent on conserved lysines in the collagenous domain: evidence for regulation of multimerization by alterations in posttranslational modifications. Richards A.A., Stephens T., Charlton H.K., Jones A., Macdonald G.A., Prins J.B., Whitehead J.P. Mol. Endocrinol. 20:1673-1687(2006) [2] Association of adiponectin mutation with type 2 diabetes: a candidate gene for the insulin resistance syndrome. Kondo H., Shimomura I., Matsukawa Y., Kumada M., Takahashi M., Matsuda M., Ouchi N., Kihara S., Kawamoto T., Sumitsuji S., Funahashi T., Matsuzawa Y. Diabetes 51:2325-2328(2002) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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