UBA1 (UBE1) Protein from MYBIOSOURCE INC.
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| Product Name | UBA1 (UBE1) Protein |
| Description | Sequence: Full Length. Description: Recombinant full-length human UBA1 (UBE1) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. Scientific Background: UBA1 or ubiquitin-like modifier activating enzyme 1 is an E1 enzyme that initiates the activation and conjugation of ubiquitin-like proteins and catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation (1). UBE1 is able to transfer ubiquitin to a wide range of E2 substrates. UBA1 protein may participate in DNA topoisomerase-2 activity (2). UBA1 complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. MW: ~145 kDa |
| Size | 0.02 mg, 0.05 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Other Names | [Homo sapiens ubiquitin like modifier activating enzyme 1 (UBA1), transcript variant 1, mRNA; Ubiquitin-like modifier-activating enzyme 1; ubiquitin-like modifier-activating enzyme 1; ubiquitin like modifier activating enzyme 1; Protein A1S9; Ubiquitin-activating enzyme E1], [CTD-2522E6.1; A1S9; A1S9T; A1ST; AMCX1; GXP1; POC20; SMAX2; UBA1A; UBE1X] |
| Gene, Accession, CAS # | [UBA1], Gene ID: 7317, NCBI: NM_003334.3, UniProt: P22314 |
| Catalog # | MBS515704 |
| Price | $270, $450 |
| Order / More Info | UBA1 (UBE1) Protein from MYBIOSOURCE INC. |
| Product Specific References | 1. Jin, J.et.al: Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging. Nature 447: 1135-1138, 2007. 2. Zacksenhaus, E.et.al: Identification of human gene complementing ts A1S9 mouse L-cell defect in DNA replication following DNA-mediated gene transfer. Somat. Cell Molec. Genet. 14: 371-379, 1988. |
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