Z-VAD-FMK from MYBIOSOURCE INC.
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| Product Name | Z-VAD-FMK |
| Description | Purity >98%. Z-VAD-FMK is a cell-permeable, irreversible pan-caspase inhibitor. Inhibits caspase processing and apoptosis induction in tumor cells in vitro (IC50 = 0.0015 - 5.8 mM). Active in vivo. MW: 467.49 |
| Size | 1 mg, 5 mg, 10 mg |
| Concentration | 0.1 mM: 21.39 mL (1 mg); 106.95 mL (5 mg); 213.91mL (10 mg). 0.5 mM: 4.28 mL (1 mg); 21.39 mL (5 mg); 42.78 mL (10 mg). 1 mM: 2.14 mL (1 mg); 10.7 mL (5 mg); 21.39 mL (10 mg). 5 mM: 0.43 mL (1 mg); 2.14 mL (5 mg); 4.28 mL (10 mg) |
| Applications | n/a |
| Other Names | n/a |
| Gene, Accession, CAS # | CAS: 187389-52-2 |
| Catalog # | MBS385773 |
| Price | $105, $180, $255 |
| Order / More Info | Z-VAD-FMK from MYBIOSOURCE INC. |
| Product Specific References | Fujiki K,.et al. Blockade of ALK4/5 signaling suppresses cadmium- and erastin-induced cell death in renal proximal tubular epithelial cells via distinct signaling mechanisms, Cell Death Differ, 2019, Feb 25 PMID: 30804470T Yamamoto,.et al. Mycoplasma pneumoniae protects infected epithelial cells from hydrogen peroxide-induced cell detachment, Cell Microbiol, 2019, 2019 PMID: 30702185D. Bosc,.et al. A new quinoline-based chemical probe inhibits the autophagy-related cysteine protease ATG4B, Sci Rep, 2018, 8: 11653 PMID: 30076329Tsukamoto H,.et al. Lipopolysaccharide (LPS)-binding protein stimulates CD14-dependent Toll-like receptor 4 internalization and LPS-induced TBK1-IKKIu-IRF3 axis activation, J Biol Chem, 2018, Jun 29;293(26):10186-10201 PMID: 29760187Hiroshi Kuribayashi,.et al. Roles of Nmnat1 in the survival of retinal progenitors through the regulation of pro-apoptotic gene expression via histone acetylation, Cell Death Dis, 2018, Sep; 9(9): 891 PMID: 30166529Matsuo J,.et al. Activation of caspase-3 during Chlamydia trachomatis-induced apoptosis at a late stage, Can J Microbiol, 2018, Oct 18:1-9 PMID: 30336068Orly Ravid,.et al. Blood-Brain Barrier Cellular Responses Toward Organophosphates: Natural Compensatory Processes and Exogenous Interventions to Rescue Barrier Properties, Front Cell Neurosci, 2018, 12: 359 PMID: 30459557Im E,.et al. Luteolin induces caspase-dependent apoptosis via inhibiting the AKT/osteopontin pathway in human hepatocellular carcinoma SK-Hep-1 cells, Life Sci, 2018, Sep 15;209:259-266 PMID: 30107166Szalai P,.et al. Nonlinear relationship between ER Ca2 depletion versus induction of the unfolded protein response, autophagy inhibition, and cell death, Cell Calcium, 2018, Dec;76:48-61 PMID: 30261424Im E,.et al. Dihydroartemisinin induced caspase-dependent apoptosis through inhibiting the specificity protein 1 pathway in hepatocellular carcinoma SK-Hep-1 cells, Life Sci, 2018, Jan 1;192:286-292 PMID: 29128513Iriyama N,.et al. The cyclin-dependent kinase 4/6 inhibitor, abemaciclib, exerts dose-dependent cytostatic and cytocidal effects and induces autophagy in multiple myeloma cells, Leuk Lymphoma, 2018, Jun;59(6):1439-1450 PMID: 28918692Birte Plitzko,.et al. The natural product mensacarcin induces mitochondrial toxicity and apoptosis in melanoma cells, J Biol Chem, 2017, Dec 22; 292(51): 21102-21116 PMID: 29074620Akashi E,.et al. Effects of galectin-9 on apoptosis, cell cycle and autophagy in human esophageal adenocarcinoma cells, Oncol Rep, 2017, Jul;38(1):506-514 PMID: 28586026 |
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