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Product Name | Recombinant Bovine Complement factor B (CFB) , partial |
Description | Purity >85% (SDS-PAGE). This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymor. MW: 85,366 Da |
Size | 0.5 mg (E. coli), 0.05 mg (Baculovirus), 0.5 mg (Yeast) |
Concentration | n/a |
Applications | n/a |
Other Names | [complement factor B; Complement factor B; complement factor B; C3/C5 convertase; EC-VMFB], [CFB; CFB; BF; BF] |
Gene, Accession, CAS # | [CFB], Gene ID: 514076, NCBI: NP_001035616.1, UniProt: P81187 |
Catalog # | MBS955969 |
Price | $990, $990, $1210 |
Order / More Info | Recombinant Bovine Complement factor B (CFB) , partial from MYBIOSOURCE INC. |
Product Specific References | n/a |