Recombinant human IL-4I1 protein from NKMAX Co. Ltd.

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Product NameRecombinant human IL-4I1 protein
DescriptionDomain: 22-567aa. Recombinant human IL-4I1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. MW: 61.8kDa (555aa). Purity > 90% by SDS-PAGE. IL-4I1, also known as FIG1, is a secreted L-amino-acid oxidase that acts as a key immunoregulator. It is highly expressed in primary metastinal B-cell lymphomas. This protein acts as a negative regultaotr of anti-tumor immunity by mediating Trp degradation via ans indole pyruvate pathway that activates the transcription factor AHR. IL-4I1-mediated Trp catabolism generates I3P, giving rise to indole metabolites and kynurenic acid, which act as ligands for AHR, a ligand-activated transcription factor that plays important roles in immunity and cancer. IL-41I also regulates M2 macrophage polarization by inhibiting T-cell activation and has antibacterial properties by inhibiting growth of Gram negative and Gram positive bacteria through the production of NH4+ and H2O2
Size10ug, 20ug, 50ug, 100ug, 250ug, 500ug, 1mg
Concentration0.25mg/ml (determined by Absorbance at 280nm)
ApplicationsSDS-PAGE, Enzyme Activity
Other NamesInterleukin 4 induced 1, FIG1, LAAO, LAO, L-amino-acid oxidase isoform 1, L-amino-acid oxidase, IL4-induced protein 1, Fig-1, IL4I1, hIL4I1
Gene, Accession, CAS #NCBI: NP_690863, UniProt: Q96RQ9
Catalog #ATGP4099
Price$160, $280, $460, $770, $1340, $2300, $3840
Order / More InfoRecombinant human IL-4I1 protein from NKMAX Co. Ltd.
Product Specific Referencesn/a
NKMAX Co. Ltd.
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124

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