Recombinant human Sirtuin 2/SIRT2 protein from NKMAX Co. Ltd.
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| Product Name | Recombinant human Sirtuin 2/SIRT2 protein |
| Description | Domain: 1-352aa. Recombinant human SIRT2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 41.6 kDa (372aa) confirmed by MALDI-TOF. Purity > 90% by SDS-PAGE. SIRT2 (NAD-dependent deacetylase sirtuin-2) is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes and are involved in diverse processes, including transcriptional regulation, cell cycle progression, DNA-damage repair and aging. SIRT2 is a NAD-dependent deacetylase, which deacetylates the 'Lys-40' of alpha-tubulin |
| Size | 10ug, 50ug |
| Concentration | 0.25mg/ml (determined by Bradford assay) |
| Applications | SDS-PAGE |
| Other Names | NAD-dependent protein deacetylase sirtuin-2, NAD-dependent protein defatty-acylase sirtuin-2, Regulatory protein SIR2 homolog 2, SIR2-like protein 2, SIR2L, SIR2L2, Sirtuin, Silent mating type information regulation 2 homolog 2 (S. cerevisiae) cerevisiae) |
| Gene, Accession, CAS # | NCBI: NP_085096, UniProt: Q8IXJ6 |
| Catalog # | ATGP0803 |
| Price | $240, $720 |
| Order / More Info | Recombinant human Sirtuin 2/SIRT2 protein from NKMAX Co. Ltd. |
| Product Specific References | Kawaguchi M, et al. A Fluorescent Probe for Imaging Sirtuin Activity in Living Cells, Based on One-Step Cleavage of the Dabcyl Quencher. (Chembiochem. 2016){https://pubmed.ncbi.nlm.nih.gov/27542094/};;Kawaguchi M, et al. Development of Peptide-Based Sirtuin Defatty-Acylase Inhibitors Identified by the Fluorescence Probe, SFP3, That Can Efficiently Measure Defatty-Acylase Activity of Sirtuin. (J Med Chem. 2019 ){https://pubmed.ncbi.nlm.nih.gov/31117516/} |
NKMAX Co. Ltd.
NKMAX Co. Ltd.
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172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124
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http://www.nkmaxbio.com
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