Recombinant human RFXANK protein from NKMAX Co. Ltd.

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Product NameRecombinant human RFXANK protein
DescriptionDomain: 1-237aa. Recombinant human RFXANK protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 28 kDa (260aa) confirmed by MALDI-TOF. Purity > 85% by SDS-PAGE. RFXANK, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Two transcript variants encoding different isoforms have been described for this gene, with only one isoform showing activation activity
Size4ug, 20ug, 100ug
Concentration0.25mg/ml (determined by Bradford assay)
ApplicationsSDS-PAGE
Other NamesDNA-binding protein RFXANK isoform b, ANKRA1, BLS, F14150_1, RFX-B
Gene, Accession, CAS #NCBI: NP_604389, UniProt: O14593
Catalog #ATGP2188
Price$80, $240, $720
Order / More InfoRecombinant human RFXANK protein from NKMAX Co. Ltd.
Product Specific Referencesn/a
NKMAX Co. Ltd.
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124

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