Recombinant human IgG1 Fc protein from NKMAX Co. Ltd.
Search, find, compare suppliers for Recombinant human IgG1 Fc protein products.
| Edit | |
|---|---|
| Product Name | Recombinant human IgG1 Fc protein |
| Description | Domain: 100-330aa. Recombinant human IgG1 Fc was expressed in HEK293 cell and purified by using conventional chromatography techniques. MW: 25.9kDa (231aa). Purity > 90% by SDS-PAGE. Immunoglobulins are membrane-bound or secreted glycoproteins produced by B lymphocytes. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as the antibody-dependent cell-mediated cytotoxicity. IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors on phagocytic cells with high affinity. IgG comprise two identical light (L) and heavy (H) chains forming a `Y?shaped' structure. It also is digested by pepsin proteolysis into two distinct fragments (Fab, Fc). Fc fragment is a homodimeric glycoprotein with one monomer consisting of two constant immunoglobulin domains (CH2, CH3) from the C?terminal half of one heavy chain. Through interaction with its ligands (FcγR, C1q and FcRn) it mediates various immune effector functions and increases the half?life of the antibody molecule. IgG Fc (recombinant) is suggested to represent a potential anti-inflammatory drug for treatment of human autoimmune diseases |
| Size | 10ug, 20ug, 50ug, 100ug, 250ug, 500ug, 1mg |
| Concentration | 1mg/ml (determined by BCA assay) |
| Applications | SDS-PAGE, Bioactivity |
| Other Names | immunoglobulin heavy chain constant region gamma 1, IGHG1, Ig gamma-1 chain C region, Ig gamma-1 chain C region EU, Ig gamma-1 chain C region KOL, Ig gamma-1 chain C region NIE |
| Gene, Accession, CAS # | NCBI: CAC20454.1, UniProt: P01857 |
| Catalog # | ATGP4094 |
| Price | $72, $124, $169, $280, $488, $839, $1398 |
| Order / More Info | Recombinant human IgG1 Fc protein from NKMAX Co. Ltd. |
| Product Specific References | n/a |
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124
salesbio@nkmax.com
http://www.nkmaxbio.com
Profile of NKMAX Co. Ltd.
Return to Products