Edit |   |
---|---|
Product Name | Recombinant human IL-3 protein |
Description | Domain: 20-152aa. Recombinant human IL-3 was expressed in E. coli and purified by using conventional chromatography after refolding of the isolated inclusion bodies in a redox buffer. MW: 17.3 kDa (154aa) confirmed by MALDI-TOF. Purity > 90% by SDS-PAGE. Interleukin-3 (IL-3) stimulates the proliferation of hematopoietic pluripotent progenitor cells. It is secreted by activated T cells to support growth and differentiation of T cells from the bone marrow in an immune response. IL-3 exerts its biological activities through binding to specific cell surface receptors. IL-3 receptor is a complex consisting of alpha and beta subunits, which in turn induces activation of JAK2/ STAT5, induction of c-myc, and activation of the Ras pathway. Human IL3 is a protein of 15-17 kDa (133 amino acids). It is synthesized as a precursor containing a hydrophobic secretory signal sequence of 19 amino acids. IL3 contains two putative glycosylation sites at positions 15 and 70 and contains a single disulfide bond (Cys16/84) |
Size | 20ug, 100ug, 500ug |
Concentration | 1mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE, Bioactivity |
Other Names | IL-3, Multipotential colony-stimulating factor(multi-CSF), Mast cell growth factor(MCGF), interleukin 3 (colony-stimulating factor, multiple), MuLTI-CSF, MCGF, multilineage-colony-stimulating factor, hematopoietic growth factor, P-cell stimulating factor, mast-cell growth factor |
Gene, Accession, CAS # | NCBI: NP_000579, UniProt: P08700 |
Catalog # | ILC0702 |
Price | $105, $320, $960 |
Order / More Info | Recombinant human IL-3 protein from NKMAX Co. Ltd. |
Product Specific References | n/a |