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Product Name | RNASEH2A cDNA |
Description | RNASEH2A is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid. This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector. |
Size | 10ug |
Concentration | n/a |
Applications | n/a |
Other Names | AGS4, JUNB, RNASEHI, RNHIA, RNHL |
Gene, Accession, CAS # | NCBI: NP_006388.2 |
Catalog # | ATGD0491 |
Price | $99 |
Order / More Info | RNASEH2A cDNA from NKMAX Co. Ltd. |
Product Specific References | n/a |