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Product Name | Recombinant mouse Adenosylhomocysteinase/AHCY protein |
Description | Domain: 1-432aa. Recombinant mouse Ahcy, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 50.2 kDa (456aa) confirmed by MALDI-TOF. Purity > 90% by SDS-PAGE. Ahcy, also known as Adenosylhomocysteinase, is an enzyme that catalyzes the reversible hydrolysis of S-sdenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). AdoHcy hydrolysis is a reversible reaction with an equilibrium favoring AdoHcy formation, but hydrolysis prevails under physiological conditions due to the rapid removal of adenosine and homocysteine. Thus, AHCY s activity in mammals is directly related to homocysteine level, an independent risk factor for vascular disease. It also functions as a regulator of biological transmethylation by controlling the concentration of AdoHcy, a potent competitive inhibitor of all S-adenosyl-L-methionine methyltransferases |
Size | 20ug, 100ug, 500ug |
Concentration | 0.25mg/ml (determined by absorbance at 280nm) |
Applications | SDS-PAGE |
Other Names | S-adenosylhomocysteine hydrolase, AdoHcyase, CUBP, Liver copper-binding protein, S-adenosyl-L-homocysteine hydrolase, SAHH |
Gene, Accession, CAS # | NCBI: NP_057870, UniProt: P50247 |
Catalog # | ATGP3650 |
Price | $80, $240, $720 |
Order / More Info | Recombinant mouse Adenosylhomocysteinase/AHCY protein from NKMAX Co. Ltd. |
Product Specific References | n/a |