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Product Name | Recombinant human IL-19 protein |
Description | Domain: 25-177aa. Recombinant human IL-19, fused to His-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques. MW: 19.1 kDa (164aa). Purity > 95% by SDS-PAGE. IL-19, also known as Interleukin-19, is a member of the IL-10 family of related cytokines, which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. This protein is an immunosuppressive cytokine that is responsible for both cell type-specific and system-specific down-regulation of inflammation, because it up-regulates IL-6 and TNF-α, and induces apoptosis through TNF-α. It binds a receptor complex consisting of the IL-20 receptor alpha (IL-20 R1) and the IL-20 receptor beta (IL-20 R2). This receptor complex is also shared by IL-20 and IL-24. IL-19-deficient animals was associated with reduced numbers of IL-6-producing macrophages in the inflamed colonic lamina propria. It may contribute to the pathogenesis of inflammatory bowel disease |
Size | 10ug, 20ug, 50ug, 100ug, 250ug, 500ug, 1mg |
Concentration | 0.5mg/ml (determined by absorbance at 280nm) |
Applications | SDS-PAGE |
Other Names | Interleukin-19, IL-19, Melanoma differentiation-associated protein-like protein, NG.1, ZMDA1, MDA1, IL-10C, IL19, Interleukin19, Macrophagleukin-19, IL-19, 2 |
Gene, Accession, CAS # | NCBI: NP_037503.2, UniProt: Q9UHD0 |
Catalog # | ATGP4024 |
Price | $150, $270, $370, $610, $1060, $1830, $3040 |
Order / More Info | Recombinant human IL-19 protein from NKMAX Co. Ltd. |
Product Specific References | n/a |