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Product Name | Recombinant human JTB protein |
Description | Domain: 31-105aa. Recombinant human JTB protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 10.7 kDa (98aa) confirmed by MALDI-TOF. Purity > 85% by SDS-PAGE. Jumping translocation breakpoint, also known as JTB, is required for normal cytokinesis during mitosis. This protein plays a role in the regulation of cell proliferation. This protein may be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. It lnhibits apoptosis induced by TGFB1. Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential |
Size | 4ug, 20ug, 100ug |
Concentration | 0.25mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | Jumping translocation breakpoint, hJT, HJTB, HSPC222, PAR |
Gene, Accession, CAS # | NCBI: NP_006685, UniProt: O76095 |
Catalog # | ATGP2782 |
Price | $80, $240, $720 |
Order / More Info | Recombinant human JTB protein from NKMAX Co. Ltd. |
Product Specific References | n/a |