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Product Name | Recombinant human SF3B14A/SF3B6 protein |
Description | Domain: 1-125aa. Recombinant human SF3B14 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 16.7 kDa (145aa) confirmed by MALDI-TOF. Purity > 95% by SDS-PAGE. SF3B14, also known as SAP14, is a 125 amino acid nuclear protein that is a component of the splicing factor 3b complex. Splicing factor 3b associates with both the u2 and u11/u12 small nuclear ribonucleoprotein complexes (u2 snRNP) of spliceosomes. Required for the splicing of pre-mRNA, SF3B14 enters the spliceosome and associates with the pre-mRNA branch site facilitating the interaction of snRNP with the branch sites of u2 and u12 of the 17S u2 and the 18S u11/u12 snRNP complex |
Size | 10ug, 50ug, 250ug |
Concentration | 0.5mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | "Splicing factor 3b subunit 6, SF3b 14 kDa subunit, Spliceosome-associated protein 14-kDa, Splicing factor 3b subunit 6 14kDa, pre mRNA branch site protein p14, P14, SF3B14a, Ht006, CGI-110, SAP14a, SAP14, SF3B14 " |
Gene, Accession, CAS # | NCBI: NP_057131, UniProt: Q9Y3B4 |
Catalog # | ATGP0920 |
Price | $80, $240, $720 |
Order / More Info | Recombinant human SF3B14A/SF3B6 protein from NKMAX Co. Ltd. |
Product Specific References | n/a |