Edit |   |
---|---|
Product Name | Recombinant human ALAD protein |
Description | Domain: 1-330aa. Recombinant human ALAD protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 38.8 kDa (354aa) confirmed by MALDI-TOF. Purity > 85% by SDS-PAGE. The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria |
Size | 10ug, 20ug, 50ug, 100ug, 250ug, 500ug, 1mg |
Concentration | 1mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | Delta-aminolevulinic acid dehydratase, ALADH, PBGS |
Gene, Accession, CAS # | NCBI: NP_000022, UniProt: P13716 |
Catalog # | ATGP1444 |
Price | $80, $140, $240, $390, $720, $1200, $1950 |
Order / More Info | Recombinant human ALAD protein from NKMAX Co. Ltd. |
Product Specific References | n/a |