Recombinant human MAPKAPK3 protein from NKMAX Co. Ltd.
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| Product Name | Recombinant human MAPKAPK3 protein |
| Description | Domain: 1-382aa. Recombinant human MAPKAPK3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 45.4 kDa (405aa) confirmed by MALDI-TOF. Purity > 95% by SDS-PAGE. MAP kinase-activated protein kinase 3, also known as MAPKAPK3, is involved in inflammatory response by regulating tumor necrosis factor (TNF) and IL6 production post-transcriptionally: acts by phosphorylating Au-rich elements (AREs) -binding proteins, such as TTP/ZFP36, leading to regulate the stability and translation of TNF and IL6 mRNAs. Phosphorylation of TTP/ZFP36, a major post-transcriptional regulator of TNF, promotes its binding to 14-3-3 proteins and reduces its ARE mRNA affinity leading to inhibition of dependent degradation of ARE-containing transcript |
| Size | 20ug, 100ug, 500ug |
| Concentration | 1mg/ml (determined by Bradford assay) |
| Applications | SDS-PAGE |
| Other Names | MAP kinase-activated protein kinase 3, 3PK, MAPKAP-K3, MAPKAP3, MAPKAPK-3, MK-3 |
| Gene, Accession, CAS # | NCBI: NP_004626, UniProt: Q16644 |
| Catalog # | ATGP1805 |
| Price | $80, $240, $720 |
| Order / More Info | Recombinant human MAPKAPK3 protein from NKMAX Co. Ltd. |
| Product Specific References | n/a |
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124
salesbio@nkmax.com
http://www.nkmaxbio.com
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