Edit |   |
---|---|
Product Name | Recombinant human IMP Dehydrogenase 1/IMPDH1 protein |
Description | Domain: 1-514aa. Recombinant human IMPDH1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 57.5 kDa (534aa) confirmed by MALDI-TOF. Purity > 95% by SDS-PAGE. Inosine-5'-monophosphate dehydrogenase 1, also known as IMPDH1 catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). Also, IMPDH1 is a ubiquitously expressed enzyme, functioning as a homotetramer, which catalyzed the rate-limiting step in de novo synthesis of guanine nucleotides. As such, it plays an important role in cyclic nucleoside metabolism within photoreceptors. Defects in the IMPDH1 gene are a cause of retinitis pigmentosa type 10 |
Size | 10ug, 50ug, 250ug |
Concentration | 0.5mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | Inosine-5'-monophosphate dehydrogenase 1, IMPD, IMPD1, LCA11, RP10, Inosine-5'-monophosphate dehydrogenase 1 IMP dehydrogenase 1. |
Gene, Accession, CAS # | NCBI: NP_001136045, UniProt: P20839 |
Catalog # | ATGP0586 |
Price | $105, $320, $960 |
Order / More Info | Recombinant human IMP Dehydrogenase 1/IMPDH1 protein from NKMAX Co. Ltd. |
Product Specific References | n/a |