Recombinant human Siglec-3/CD33 protein from NKMAX Co. Ltd.

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Product NameRecombinant human Siglec-3/CD33 protein
DescriptionDomain: 18-259aa. Recombinant human CD33, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. MW: 54 kDa (484aa). Purity > 90% by SDS-PAGE. CD33, also known as myeloid cell surface antigen CD33 isoform 1, is a member of the Ig superfamily that is restricted to cells of the myelomonocytic lineage but whose functions and binding properties are unknown. It can function as a sialic acid-dependent cell adhesion molecule and that binding can be modulated by endogenous sialoglycoconjugates when it is expressed in a plasma membrane. It is usually considered myeloid-specific, but it can also be found on some lymphoid cells. It contains immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that are implicated in inhibition of cellular activity. It has been identified to modulate the risk of Alzheimer's disease (AD) in several recent genome-wide association studies (GWAS) in Caucasians
Size10ug, 50ug, 250ug
Concentration0.25mg/ml (determined by absorbance at 280nm)
ApplicationsSDS-PAGE
Other NamesSIGLEC-3, SIGLEC3, Sialic acid-binding Ig-like lectin 3, p67, Myeloid cell surface antigen CD33 isoform 1, Myeloid cell surface antigen CD33, FLJ00391, CD33 molecule, CD33
Gene, Accession, CAS #NCBI: NP_001763, UniProt: P20138
Catalog #ATGP3687
Price$105, $320, $1280
Order / More InfoRecombinant human Siglec-3/CD33 protein from NKMAX Co. Ltd.
Product Specific Referencesn/a
NKMAX Co. Ltd.
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124

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