Recombinant human SNURF protein from NKMAX Co. Ltd.

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Product NameRecombinant human SNURF protein
DescriptionDomain: 1-71aa. Recombinant human SNuRF protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 10.8 kDa (94aa) confirmed by MALDI-TOF. Purity > 90% by SDS-PAGE. SNuRF is a highly basic protein localized to the nucleus. The evolutionarily constrained open reading frame is found on a bicistronic transcript which has a downstream ORF encoding the small nuclear ribonucleoprotein polypeptide N. The upstream coding region utilizes the first three exons of the transcript, a region that has been identified as an imprinting center. Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region but the full-length nature of these transcripts has not been determined. An alternate exon has been identified that substitutes for exon 4 and leads to a truncated, monocistronic transcript. Alternative splicing or deletion caused by a translocation event in the 5' uTR or coding region of this gene leads to Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. The function of this protein is not yet known
Size10ug, 50ug, 250ug
Concentration0.25mg/ml (determined by Bradford assay)
ApplicationsSDS-PAGE
Other NamesSNRPN upstream reading frame protein, Small nuclear ring finger protein
Gene, Accession, CAS #NCBI: NP_073715, UniProt: Q9Y675
Catalog #ATGP2528
Price$105, $320, $960
Order / More InfoRecombinant human SNURF protein from NKMAX Co. Ltd.
Product Specific Referencesn/a
NKMAX Co. Ltd.
NKMAX Co. Ltd.
NKMAX Co. Ltd.
6F, SNUH Health Care Innovation Park
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do 13605 REPUBLIC OF KOREA
P: +82-31-8017-8114
F: +82-31-8017-8124

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