Edit |   |
---|---|
Product Name | Recombinant human Ketohexokinase protein |
Description | Domain: 1-298aa. Recombinant human Ketohexokinase was expressed in E. coli and purified by using conventional chromatography. MW: 32.7 kDa (298aa) confirmed by MALDI-TOF. Purity > 90% by SDS-PAGE. Ketohexokinase is an enzyme that catalyzes the phosphorylation of fructose to produce fructose-1-phosphate, leading to consumption of ATP, formation of AMP. This protein initiates first step in the metabolism of dietary fructose and is an important regulator of hepatic glucose metabolism. It is highly found in liver, renal cortex, and small intestine. Its deficiency causes the benign hereditary metabolic disorder essential fructosuria, leading to fructose being excreted in the urine |
Size | 20ug, 100ug, 500ug |
Concentration | 1mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | KHK, Hepatic fructokinase, EC 2.7.1.3, Hepatic fructokinase, ketohexokinase, Ketohexokinase isoform a, |
Gene, Accession, CAS # | NCBI: AAH06233, UniProt: P50053 |
Catalog # | ATGP0437 |
Price | $70, $210, $625 |
Order / More Info | Recombinant human Ketohexokinase protein from NKMAX Co. Ltd. |
Product Specific References | Wuest M, et al. Radiopharmacological evaluation of 6-deoxy-6-[18F]fluoro-D-fructose as a radiotracer for PET imaging of GLUT5 in breast cancer. (Nucl Med Biol. 2011){https://pubmed.ncbi.nlm.nih.gov/21531283/} |