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Product Name | Recombinant human Smad3 protein |
Description | Domain: 1-425aa. Recombinant SMAD3 protein was expressed in E. coli and purified by using conventional chromatography techniques. MW: 50.2 kDa (445aa) confirmed by MALDI-TOF. Purity > 90% by SDS-PAGE. SMAD3, also known as mothers against decapentaplegic homolog 3, belongs to the SMAD family of proteins that mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. Small moleucule inhibitors of Smad3 may have tremendous clinical potential in the treatment of pathological fibrotic diseases |
Size | 20ug, 100ug, 500ug |
Concentration | 0.5mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | Mothers against decapentaplegic homolog 3, HSPC193, HsT17436, JV15-2, MADH3, Mothers against decapentaplegic homolog 3 DKFZP586N0721, DKFZp686J10186, hMAD 3, hSMAD3, MAD (mothers against decapentaplegic Drosophila) homolog 3, HST17436, JV15 2, JV152, MAD3, MADH 3, MGC60396, Mothers against DPP homolog 3, SMA and MAD related protein 3, SMAD, SMAD 3, SMAD3, |
Gene, Accession, CAS # | NCBI: NP_005893, UniProt: P84022 |
Catalog # | ATGP0421 |
Price | $70, $210, $625 |
Order / More Info | Recombinant human Smad3 protein from NKMAX Co. Ltd. |
Product Specific References | n/a |