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Product Name | Recombinant human Serpin C1/Antithrombin-III protein |
Description | Domain: 33-464aa. Recombinant human SERPINC1 protein, fused to His-tag at N-terminus, was expressed in E. coli. MW: 51.4 kDa (455aa). Purity > 85% by SDS-PAGE. Antithrombin-III precursor, also known as SERPINC1, is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The inhibitory activity of SERPINC1 is amplified in the presence of heparin. SERPINC1 inhibits Thrombin and Factors IXa, Xa and XIa. Defects in the gene SERPINC1, which encodes for ATIII, can cause ATIII deficiency, an autosomal dominant disease which is a risk factor for hereditary thrombophilia |
Size | 20ug, 100ug, 500ug |
Concentration | 0.5mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE, Denatured |
Other Names | Antithrombin-III precursor, AT3, AT3D, ATIII, THPH7 |
Gene, Accession, CAS # | NCBI: NP_000479, UniProt: P01008 |
Catalog # | ATGP2571 |
Price | $80, $240, $720 |
Order / More Info | Recombinant human Serpin C1/Antithrombin-III protein from NKMAX Co. Ltd. |
Product Specific References | n/a |