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Product Name | Recombinant human IL-1Ra/IL1RN protein |
Description | Domain: 26-177aa. Recombinant human IL-1RA was expressed in E. coli and purified by using conventional chromatography techniques. MW: 17.2 kDa (153aa), confirmed by MALDI-TOF. Purity > 95% by SDS - PAGE. IL-1RA/IL-1F3, also known as interleukin-1 receptor antagonist, is a glycosylated protein and a powerful anti-inflammatory agent. IL?1RA is a pan?physiological inhibitor of IL?1 that prevents the activation of IL?1 receptors by inhibiting IL?1 binding to its receptors. It can inhibit angiogenesis by blocking the activation of the IL?1α/PI3K/NF?κB pathway in IL?1?producing human colon cancer cells. Also, Several autoimmune and inflammatory diseases have been associated with an allelic polymorphism of the IL-1RA |
Size | 10ug, 20ug, 50ug, 100ug, 250ug, 500ug, 1mg |
Concentration | 1mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE, Bioactivity |
Other Names | Interleukin-1 receptor antagonist protein, IL-1RN, IL-1ra, IRAP, ICIL-1RA, IL1 inhibitor, IL1F3, IL1RA |
Gene, Accession, CAS # | NCBI: NP_776214, UniProt: P18510 |
Catalog # | ATGP3934 |
Price | $70, $120, $160, $270, $470, $810, $1350 |
Order / More Info | Recombinant human IL-1Ra/IL1RN protein from NKMAX Co. Ltd. |
Product Specific References | n/a |