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Product Name | Recombinant human RGS1 protein |
Description | Domain: 1-209aa. Recombinant human RGS1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 26.4 kDa (233aa) confirmed by MALDI-TOF. Purity > 90% by SDS-PAGE. RGS1 is a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal |
Size | 20ug, 100ug, 500ug |
Concentration | 0.25mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | Regulator of G-protein signaling 1, 1R20; BL34; IER1; IR20 |
Gene, Accession, CAS # | NCBI: NP_002913, UniProt: Q08116 |
Catalog # | ATGP1572 |
Price | $105, $320, $960 |
Order / More Info | Recombinant human RGS1 protein from NKMAX Co. Ltd. |
Product Specific References | n/a |