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Product Name | Recombinant human LAMTOR4 protein |
Description | Domain: 1-99aa. Recombinant human LAMTOR4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 13.1 kDa (122aa) confirmed by MALDI-TOF. Purity > 85% by SDS-PAGE. LAMTOR4 is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated |
Size | 4ug, 20ug, 100ug |
Concentration | 0.25mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | Ragulator complex protein LAMTOR4, C7orf59 |
Gene, Accession, CAS # | NCBI: NP_001008396, UniProt: Q0VGL1 |
Catalog # | ATGP2791 |
Price | $80, $240, $720 |
Order / More Info | Recombinant human LAMTOR4 protein from NKMAX Co. Ltd. |
Product Specific References | n/a |