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Product Name | GSKIP cDNA |
Description | GSKIP encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene. This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector. |
Size | 10ug |
Concentration | n/a |
Applications | n/a |
Other Names | C14orf129, HSPC210 |
Gene, Accession, CAS # | NCBI: NP_057556.2 |
Catalog # | ATGD0167 |
Price | $99 |
Order / More Info | GSKIP cDNA from NKMAX Co. Ltd. |
Product Specific References | n/a |