Edit |   |
---|---|
Product Name | Recombinant human IL-4R alpha/IL4R protein |
Description | Domain: 26-232aa. Recombinant human IL4R, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. MW: 24.7 kDa (215aa). Purity > 95% by SDS-PAGE. IL4R, also known as interleukin 4 receptor subunit alpha isoform, is a pleiotropic cytokine produced by T lymphocytes. It plays an important role in immune responsiveness by regulating proliferation and differentiation of a variety of lymphoid and myeloid cells via binding to high affinity receptors. It markedly inhibits IL-1 production by highly purified normal human monocytes. It has been demonstrated to affect the growth of different human malignancies including pancreatic cancer cells. It plays an important role in Th2-biased immune responses, alternative macrophage activation, mucosal immunity, allergic inflammation, tumor progression, and atherogenesis |
Size | 10ug, 50ug, 250ug |
Concentration | 0.25mg/ml (determined by BCA assay) |
Applications | SDS-PAGE |
Other Names | Interleukin 4 receptor subunit alpha isoform, IL4R, CD124, IL-4RA, IL4RA, IL-4 receptor subunit alpha; IL-4R subunit alpha |
Gene, Accession, CAS # | NCBI: NP_000409, UniProt: P24394 |
Catalog # | ATGP3710 |
Price | $105, $320, $1280 |
Order / More Info | Recombinant human IL-4R alpha/IL4R protein from NKMAX Co. Ltd. |
Product Specific References | n/a |