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Product Name | Recombinant human DPH2 protein |
Description | Domain: 1-489aa. Recombinant human DPH2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. MW: 53.1 kDa (497aa). Purity > 85% by SDS-PAGE. DPH2, also known as diphthamide biosynthesis protein 2, is a homodimer and each of its monomers can bind a [4Fe-4S] cluster. It is the target of ADP ribosylating diphtheria toxin (DT) and Pseudomonas exotoxin A (PE). It was identified by its ability to complement a diphthamide mutant strain, and thus functions in diphthamide biosynthesis. Its loss pre-activates NF-kB and death receptor pathways and renders MCF7 cells hypersensitive to tumor necrosis factor |
Size | 10ug, 50ug |
Concentration | 0.5mg/ml (determined by absorbance at 280nm) |
Applications | SDS-PAGE |
Other Names | Diphthamide biosynthesis protein 2, DPH2, DPH2L2 |
Gene, Accession, CAS # | NCBI: NP_001375, UniProt: Q9BQC3 |
Catalog # | ATGP3582 |
Price | $240, $960 |
Order / More Info | Recombinant human DPH2 protein from NKMAX Co. Ltd. |
Product Specific References | n/a |