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Product Name | Recombinant human SHP-2/PTPN11 protein |
Description | Domain: 1-593aa. Recombinant human SHP-2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. MW: 69.1kDa (602aa). Purity > 90% by SDS-PAGE. SHP-2, also known as, tyrosine-protein phospatase non-receptor type 11(PTPN11), is a member of the protein tyrosine phosphatase (PTP) family containing two Src homology 2 domains. This protein dephosphorylates tyrosine residues in proteins. It plays a stimulatory role in activation of the Erk/MAP kinase pathway by receptor tyrosine kinase signaling. Mutations in this protein are a cause of Noonan syndrome as well as acute myeloid leukemia |
Size | 10ug, 20ug, 50ug, 100ug, 250ug, 500ug, 1mg |
Concentration | 1mg/ml (determined by Absorbance at 280nm) |
Applications | SDS-PAGE, Enzyme Activity |
Other Names | Protein tyrosine phosphatase non-receptor type 11, NS1, Noonan syndrome 1, SH2 domain-containing protein tyrosine phosphatase 2, SHP-2, Protein-tyrosine phosphatase 1D, PTP-1D, Protein-tyrosine phosphatase 2C, PTP-2C, PTP2C, SHP2, BPTP3, SH-PTP2 |
Gene, Accession, CAS # | NCBI: NP_002825, UniProt: Q06124 |
Catalog # | ATGP3943 |
Price | $90, $170, $220, $370, $650, $1110, $1860 |
Order / More Info | Recombinant human SHP-2/PTPN11 protein from NKMAX Co. Ltd. |
Product Specific References | n/a |