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Product Name | Recombinant human SCO2 protein |
Description | Domain: 42-266aa. Recombinant human SCO2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 27.4 kDa (246aa) confirmed by MALDI-TOF. Purity > 90% by SDS-PAGE. SCO2 protein belongs to the SCO1/2 family of proteins. Both SCO1 and SCO2 proteins are located on the inner membrane of the mitochondria and plays a crucial role in copper insertion or transport to the active site of cytochrome c oxidase (COX). Defects in SCO2 are the cause of fatal infantile cardioencephalomyopathy with cytochrome c oxidase deficiency (FIC). This disease is characterized by hypertrophic cardiomyopathy, lactic acidosis, and gliosis. Heart and skeletal muscle show reductions in cytochrome c oxidase (COX) activity, whereas liver and fibroblasts show mild COX deficiencies |
Size | 10ug, 50ug, 250ug |
Concentration | 0.5mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | Protein SCO2 homolog mitochondrial, Protein SCO2 homolog mitochondrial, SCO1L |
Gene, Accession, CAS # | NCBI: NP_005129, UniProt: O43819 |
Catalog # | ATGP0867 |
Price | $105, $320, $960 |
Order / More Info | Recombinant human SCO2 protein from NKMAX Co. Ltd. |
Product Specific References | n/a |